Description

2-Chloro-6,7,8,9-Tetrahydro-5H-Pyrido[2,3-D]Azepine is a high-value, heterocyclic organic compound with the CAS number 1003587-71-0, serving as a critical building block in advanced pharmaceutical synthesis. Its unique fused azepine-pyridine structure makes it an essential intermediate for developing novel active pharmaceutical ingredients (APIs) and bioactive molecules. This compound is primarily targeted at research institutions and pharmaceutical companies engaged in medicinal chemistry, drug discovery, and process development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of complex drug candidates targeting central nervous system (CNS) disorders, oncology, and other therapeutic areas.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Used in the research and development stages for creating new active pharmaceutical ingredients, particularly those with fused polycyclic structures.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up activities.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2-Chloro-6,7,8,9-Tetrahydro-5H-Pyrido[2,3-D]Azepine
CAS No.	1003587-71-0
Molecular Formula	C10H13ClN2
Molecular Weight	196.68 g/mol
Synonyms	2-Chloro-6,7,8,9-tetrahydro-5H-pyrido[2,3-d]azepine; 5H-Pyrido[2,3-d]azepine, 2-chloro-6,7,8,9-tetrahydro-; 2-Chloro-5,6,7,8-tetrahydro-9H-pyrido[2,3-d]azepine; 2-Chloro-6,7,8,9-tetrahydro-5H-1,4-diazepino[6,7,1-hi]indole (incorrect but common misnomer); 1003587-71-0; Azepine intermediate; Pyridoazepine chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-6,7,8,9-Tetrahydro-5H-Pyrido[2,3-D]Azepine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, meeting the stringent requirements of pharmaceutical R&D. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines where applicable, and our quality systems are designed to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.