Description

3-Bromo-4-Chloro-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-6-Amine is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because it serves as a critical scaffold for developing novel pharmaceutical candidates, particularly in kinase inhibitor research. It is primarily needed by medicinal chemists and R&D teams in the pharmaceutical, agrochemical, and life science industries for lead optimization and structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs, especially protein kinase inhibitors for oncology and inflammatory diseases.
• Medicinal Chemistry Research: Used extensively in lead compound discovery and optimization programs to explore new chemical entities (NCEs).
• Biochemical Probe Development: Serves as a core structure for creating selective probes to study enzyme function and cellular signaling pathways.
• Agrochemical Synthesis: Potential intermediate in the development of new herbicides or fungicides, leveraging its heterocyclic activity.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery pipelines for global clients.
• Academic Research: Utilized in university and institutional labs for fundamental studies in heterocyclic chemistry and drug design methodologies.

Basic Information

Product Name	3-Bromo-4-Chloro-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-6-Amine
CAS No.	1003298-80-3
Molecular Formula	C7H6BrClN5
Molecular Weight	291.51 g/mol
Synonyms	3-Bromo-4-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidin-6-amine; 1-Methyl-3-bromo-4-chloro-1H-pyrazolo[3,4-d]pyrimidin-6-amine; 6-Amino-3-bromo-4-chloro-1-methyl-1H-pyrazolo[3,4-d]pyrimidine; 3-Bromo-4-chloro-1-methyl-6-amino-1H-pyrazolo[3,4-d]pyrimidine; 1003298-80-3; BCPMPA; Pyrazolo[3,4-d]pyrimidine, 3-bromo-4-chloro-1-methyl-6-amino-
EINECS	Contact for details

Quality Control

Our 3-Bromo-4-Chloro-1-Methyl-1H-Pyrazolo[3,4-D]Pyrimidin-6-Amine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.