Description

2,2-Difluoro-6-Nitro-2H-Benzo[B][1,4]Oxazin-3(4H)-One is a high-purity, specialized heterocyclic building block featuring a difluoro-substituted oxazine core. This compound is valued for its unique molecular architecture, which is critical for introducing specific structural motifs and reactivity in advanced synthetic pathways. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the difluoro and nitro groups contribute to biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for developing advanced organic materials, such as dyes, pigments, and functional polymers with specific electronic or optical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies, heterocyclic chemistry exploration, and the synthesis of complex molecular libraries for screening.
• Fluorinated Compound Development: Acts as a versatile scaffold for introducing fluorine atoms into target molecules, a common strategy in medicinal chemistry to modulate potency, lipophilicity, and metabolic profile.

Basic Information

Product Name	2,2-Difluoro-6-Nitro-2H-Benzo[B][1,4]Oxazin-3(4H)-One
CAS No.	1002726-49-9
Molecular Formula	C8H4F2N2O4
Molecular Weight	230.13 g/mol
Synonyms	2,2-Difluoro-6-nitro-2H-1,4-benzoxazin-3(4H)-one; 6-Nitro-2,2-difluoro-2H-benzo[b][1,4]oxazin-3(4H)-one; 2,2-Difluoro-6-nitro-4H-benzo[b][1,4]oxazin-3-one; 2,2-Difluoro-6-nitro-3,4-dihydro-2H-benzo[b][1,4]oxazin-3-one; 1002726-49-9; Difluoronitrobenzoxazinone; Benzoxazinone, 2,2-difluoro-6-nitro-3,4-dihydro-
EINECS	Contact for details

Quality Control

Our 2,2-Difluoro-6-Nitro-2H-Benzo[B][1,4]Oxazin-3(4H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports applications requiring high-purity intermediates for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0% Any single unknown impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.