Description

5,8-Dioxa-Spiro[3.4]Octane-2-Carboxylic Acid is a high-value, multifunctional spirocyclic building block and intermediate in advanced organic synthesis. Its unique spirocyclic acetal structure with a carboxylic acid handle makes it a versatile precursor for constructing complex molecular architectures. This compound is primarily sought after by research and development chemists in the pharmaceutical, agrochemical, and material science industries for applications in drug discovery, ligand design, and polymer modification.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging its spirocyclic scaffold for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chelating ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer & Material Science: Incorporated as a monomer or cross-linking agent to create specialty polymers with unique thermal and mechanical properties.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes and protein interactions.
• Fine Chemical Synthesis: Acts as a versatile intermediate for synthesizing complex natural products and other fine chemicals.

Basic Information

Product Name	5,8-Dioxa-Spiro[3.4]Octane-2-Carboxylic Acid
CAS No.	1001907-64-7
Molecular Formula	C7H10O4
Molecular Weight	158.15 g/mol
Synonyms	2-Carboxy-5,8-dioxaspiro[3.4]octane; 5,8-Dioxaspiro[3.4]octane-2-carboxylic acid; Spiro[1,3-dioxolane-2,1'-cyclopropane]-4-carboxylic acid; 1-Oxaspiro[2.3]hexane-5-carboxylic acid, 4,7-dihydro-; Cyclopropanespiro-2'-(1,3-dioxolane)-4-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 5,8-Dioxa-Spiro[3.4]Octane-2-Carboxylic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency suitable for research and scale-up applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.