Description

1,3-Azetidinedicarboxylic Acid, 1-(1,1-Dimethylethyl) Ester, 3-Hydrazide is a high-purity, specialized heterocyclic building block of significant interest in advanced organic synthesis. Its unique structure, featuring both a protected carboxylic acid and a reactive hydrazide moiety, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly those containing β-lactam or constrained heterocyclic scaffolds.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its reactive sites for structure-activity relationship (SAR) studies.
• Peptidomimetic Synthesis: Serves as a constrained amino acid surrogate for creating conformationally restricted peptides with enhanced metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized chelating ligands and organocatalysts for asymmetric synthesis.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polymers with unique thermal or mechanical properties.
• Academic & Contract Research: Essential reagent in university and CRO laboratories for methodological development and exploratory chemistry projects.

Basic Information

Item	Details
Product Name	1,3-Azetidinedicarboxylic Acid, 1-(1,1-Dimethylethyl) Ester, 3-Hydrazide
CAS No.	1001907-44-3
Molecular Formula	C10H17N3O4
Molecular Weight	243.26 g/mol
Synonyms	tert-Butyl 3-hydrozinocarbonylazetidine-1-carboxylate; 1-(tert-Butoxycarbonyl)azetidine-3-carboxylic hydrazide; 1-Boc-azetidine-3-carbohydrazide; Azetidine-1,3-dicarboxylic acid, 1-(1,1-dimethylethyl) ester, 3-hydrazide; 3-Hydrazinylcarbonyl-1-azetidinecarboxylic acid tert-butyl ester; Boc-Azetidine-3-Carbohydrazide; 1-N-Boc-3-carbohydrazido-azetidine
EINECS	Contact for details

Quality Control

Every batch of 1,3-Azetidinedicarboxylic Acid, 1-(1,1-Dimethylethyl) Ester, 3-Hydrazide is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from heat sources and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.