Description

4-(1-Azetidinyl)-Cyclohexanamine 2Hcl is a high-purity, versatile organic building block featuring a unique azetidine-cyclohexylamine scaffold. This compound is critical for medicinal chemistry research and pharmaceutical development, enabling the synthesis of novel bioactive molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Medicinal Chemistry Scaffold: Used to introduce constrained azetidine and cyclohexylamine motifs to explore structure-activity relationships (SAR) and improve pharmacokinetic properties.
• Agrochemical Research: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand Synthesis: Utilized in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Acts as a core structure for creating tool compounds to study biological pathways and protein function.
• Custom Synthesis & Contract Manufacturing: A starting material for bespoke chemical synthesis services targeting niche applications.

Basic Information

Product Name	4-(1-Azetidinyl)-Cyclohexanamine 2Hcl
CAS No.	1001347-27-8
Molecular Formula	C9H20Cl2N2
Molecular Weight	227.18 g/mol
Synonyms	4-(Azetidin-1-yl)cyclohexanamine dihydrochloride; 4-(1-Azetidinyl)cyclohexanamine hydrochloride (1:2); Cyclohexanamine, 4-(1-azetidinyl)-, hydrochloride (1:2); 4-Azetidin-1-yl-cyclohexylamine dihydrochloride; 4-(Azetidin-1-yl)cyclohexan-1-amine dihydrochloride; N-Cyclohexylazetidine dihydrochloride; 1-(4-Aminocyclohexyl)azetidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 4-(1-Azetidinyl)-Cyclohexanamine 2Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with data from techniques including HPLC, NMR, and mass spectrometry. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical development materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.