Description

2-o-(p-Nitrophenyl)-α-D-n-Glycolylneuraminic Acid Methyl Ester is a specialized, high-purity chemical derivative of neuraminic acid, a key component in sialic acid research. This compound matters as a critical biochemical tool for studying glycosylation, enzyme kinetics, and carbohydrate-protein interactions. It is primarily needed by research institutions, pharmaceutical R&D departments, and diagnostic manufacturers focused on glycobiology, antiviral research, and the development of novel therapeutic agents.

Application

• Biochemical Research: A key intermediate and substrate for studying sialidases (neuraminidases) and sialyltransferases in glycobiology.
• Pharmaceutical Development: Used in the synthesis and screening of potential neuraminidase inhibitors for antiviral applications.
• Diagnostic Reagent Synthesis: Serves as a precursor for labeled probes and assay components in diagnostic kits targeting sialic acid-related pathways.
• Enzyme Characterization: Employed as a chromogenic or fluorogenic substrate for the kinetic analysis and inhibition profiling of glycosyl hydrolases.
• Glycoconjugate Chemistry: Acts as a building block for the chemical and enzymatic synthesis of complex oligosaccharides and glycoconjugates.
• Cell Biology Studies: Utilized in research exploring cell surface sialylation and its role in cell signaling, adhesion, and immune response.

Basic Information

Product Name	2-o-(p-Nitrophenyl)-α-D-n-Glycolylneuraminic Acid Methyl Ester
CAS No.	1000890-53-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	p-Nitrophenyl N-Acetylneuraminate Methyl Ester; p-Nitrophenyl 5-Acetamido-3,5-dideoxy-D-glycero-D-galacto-non-2-ulopyranosidonic Acid Methyl Ester; 2-O-(4-Nitrophenyl)-α-D-N-glycolylneuraminic Acid Methyl Ester; Neu5Gc-α-(4-Nitrophenyl)-Methyl Ester; 4-Nitrophenyl Neu5Gc Methyl Ester; Chromogenic Neuraminic Acid Substrate; Sialic Acid Derivative pNP Ester
EINECS	Contact for details

Quality Control

Our 2-o-(p-Nitrophenyl)-α-D-n-Glycolylneuraminic Acid Methyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.