Description

2-o-(p-Nitrophenyl)-α-D-n-Glycolylneuraminic Acid CAS NO 1000890-36-7 is a specialized sialic acid derivative, a critical building block in advanced biochemical research and pharmaceutical development. This compound is valued for its role as a key intermediate in the synthesis of complex glycoconjugates and enzyme substrates. It is primarily utilized by researchers and manufacturers in the fields of glycobiology, enzymology, and medicinal chemistry for investigating and developing novel therapeutics and diagnostic tools.

Application

• Enzyme Substrate Development: Used as a precursor or intermediate in the synthesis of specific substrates for neuraminidase (sialidase) and other glycosidase enzymes.
• Glycoconjugate Synthesis: Serves as a key building block for the chemical and enzymatic synthesis of complex oligosaccharides, glycopeptides, and glycolipids.
• Medicinal Chemistry Research: Employed in the design and development of sialic acid-based inhibitors for viral and bacterial pathogens, including influenza.
• Biochemical Assays: Utilized in high-throughput screening (HTS) assays to identify and characterize enzyme activity and inhibitors.
• Diagnostic Reagent Intermediate: Acts as a critical intermediate in the production of reagents for diagnostic kits targeting sialic acid-related biological processes.
• Academic & Industrial R&D: Fundamental research tool in universities and biotech companies for studying cell surface recognition, signaling, and carbohydrate-protein interactions.

Basic Information

Item	Details
Product Name	2-o-(p-Nitrophenyl)-α-D-n-Glycolylneuraminic Acid
CAS No.	1000890-36-7
Molecular Formula	C17H22N2O12
Molecular Weight	446.36 g/mol
Synonyms	p-Nitrophenyl 5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosidonic acid; 2-O-(4-Nitrophenyl)-α-D-N-glycolylneuraminic acid; 4-Nitrophenyl N-acetyl-α-neuraminide derivative; Sialic acid p-nitrophenyl glycoside; Neu5Gc-α-pNP; Glycolylneuraminic acid p-nitrophenyl derivative
EINECS	Contact for details

Quality Control

Our 2-o-(p-Nitrophenyl)-α-D-n-Glycolylneuraminic Acid is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and specific tests for residual solvents and moisture. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.