Description

Quinolin-6-Yl 2,2,2-Trifluoroacetate is a specialized chemical building block featuring a quinoline core functionalized with a trifluoroacetate ester group. This compound is of significant value in advanced organic synthesis, particularly in pharmaceutical research and development, where it serves as a key intermediate for constructing complex molecules. Its primary utility lies in the synthesis of active pharmaceutical ingredients (APIs) and agrochemicals, making it essential for R&D laboratories and fine chemical manufacturers targeting high-value markets.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those containing the quinoline pharmacophore for therapeutic applications.
• Agrochemical Research: Used in the development of advanced pesticides, herbicides, and fungicides where the quinoline structure imparts specific biological activity.
• Material Science: Serves as a precursor for the development of specialty chemicals, including ligands for catalysis and monomers for advanced polymers.
• Organic Synthesis: Employed in academic and industrial research laboratories for constructing complex heterocyclic compounds and in method development.
• Fluorine Chemistry: The trifluoroacetate group makes it a valuable reagent for introducing fluorine atoms or fluorinated motifs into target molecules, a key strategy in modern medicinal chemistry.

Basic Information

Product Name	Quinolin-6-Yl 2,2,2-Trifluoroacetate
CAS No.	1000775-18-7
Molecular Formula	C₁₁H₆F₃NO₂
Molecular Weight	241.17 g/mol
Synonyms	6-Quinolyl 2,2,2-Trifluoroacetate; 6-Hydroxyquinoline Trifluoroacetate Ester; 2,2,2-Trifluoroacetic Acid Quinolin-6-Yl Ester; Quinolin-6-ol Trifluoroacetate; 6-Quinolinol, 2,2,2-trifluoroacetate; 6-Quinolyl Trifluoroacetate; 6-(Trifluoroacetoxy)quinoline
EINECS	Contact for details

Quality Control

Our Quinolin-6-Yl 2,2,2-Trifluoroacetate is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.