Description

tert-Butyl 3-Bromo-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate is a high-value pharmaceutical intermediate and versatile synthetic building block. This compound is crucial for medicinal chemistry research and development, particularly in the synthesis of complex heterocyclic molecules. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting neurological and cardiovascular disorders.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Serves as a building block for creating novel pesticides and herbicides with thienopyridine-based structures.
• Chemical Synthesis: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for introducing functional complexity.
• API (Active Pharmaceutical Ingredient) Manufacturing: An important intermediate in the multi-step synthesis of complex active pharmaceutical ingredients.

Basic Information

Product Name	tert-Butyl 3-Bromo-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate
CAS No.	1000577-81-0
Molecular Formula	C12H14BrNO2S
Molecular Weight	316.21 g/mol
Synonyms	tert-Butyl 3-bromo-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-5-carboxylate; 3-Bromo-5-[(tert-butoxy)carbonyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridine; 5-(tert-Butoxycarbonyl)-3-bromo-6,7-dihydro-4H-thieno[3,2-c]pyridine; 3-Bromo-6,7-dihydro-4H-thieno[3,2-c]pyridine-5-carboxylic acid tert-butyl ester; BOC-3-Bromo-4,5,6,7-tetrahydrothieno[3,2-c]pyridine
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Bromo-6,7-dihydrothieno[3,2-c]pyridine-5(4H)-carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.