Description

(3-Trifluoromethyl-Pyridin-2-Yl)-Acetic Acid is a high-value pyridine derivative and fluorinated building block essential for advanced organic synthesis. This compound matters as a key intermediate for introducing the trifluoromethylpyridine moiety, a privileged scaffold known to enhance the biological activity, metabolic stability, and lipophilicity of target molecules. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of new active ingredients, including potential drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas targeting the central nervous system, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethylpyridine group can improve efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated organic materials and electronic chemicals for specialty applications.
• Custom Synthesis & Contract Manufacturing: A key starting material for fine chemical manufacturers offering bespoke synthesis services to the life science industry.

Basic Information

Product Name	(3-Trifluoromethyl-Pyridin-2-Yl)-Acetic Acid
CAS No.	1000521-27-6
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2-(3-(Trifluoromethyl)pyridin-2-yl)acetic acid; [3-(Trifluoromethyl)-2-pyridyl]acetic acid; (3-Trifluoromethyl-2-pyridyl)acetic Acid; α-Carboxy-3-(trifluoromethyl)-2-pyridineacetic acid; 3-Trifluoromethylpyridine-2-acetic acid; 2-Pyridineacetic acid, 3-(trifluoromethyl)-; (3-CF3-Pyridin-2-yl)-Acetic Acid
EINECS	Contact for details

Quality Control

Our (3-Trifluoromethyl-Pyridin-2-Yl)-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.