Description

1,2-Bis((2S,5S)-2,5-Diisopropylphospholano)Benzene(Cyclooctadiene)Rhodium(I) Tetrafluoroborate, 97% is a high-purity, chiral organometallic complex widely recognized as a highly efficient and enantioselective catalyst precursor. Its core value proposition lies in enabling asymmetric hydrogenation and other transition metal-catalyzed reactions critical for producing single-enantiomer intermediates in pharmaceutical and fine chemical synthesis. This product is essential for R&D scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-performance catalysts to develop chiral active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Asymmetric Hydrogenation Catalyst: A premier catalyst precursor for the enantioselective hydrogenation of prochiral olefins, enamines, and ketones in pharmaceutical intermediate synthesis.
• Pharmaceutical API Manufacturing: Critical for the production of single-enantiomer drugs, including β-blockers, antibiotics, and antiviral agents, ensuring high optical purity.
• Fine Chemical Synthesis: Used in the synthesis of complex chiral molecules for agrochemicals, flavors, and fragrances.
• Academic & Industrial R&D: A valuable tool for method development and exploring new asymmetric transformations in academic laboratories and corporate R&D centers.
• Process Chemistry Optimization: Employed for scaling up enantioselective reactions from laboratory to pilot plant and commercial production.
• Ligand Evaluation & Catalyst Screening: Serves as a benchmark or starting material for evaluating new chiral phosphine ligands and catalytic systems.

Basic Information

Product Name	1,2-Bis((2S,5S)-2,5-Diisopropylphospholano)Benzene(Cyclooctadiene)Rhodium(I) Tetrafluoroborate, 97%
CAS No.	1000393-36-1
Molecular Formula	C34H56BF4P2Rh
Molecular Weight	722.45 g/mol
Synonyms	(1,5-Cyclooctadiene)((2S,5S)-2,5-Diisopropylphospholano-κP)benzene-1,2-diyl)rhodium(I) Tetrafluoroborate; Rhodium(I) (1,5-cyclooctadiene)((2S,5S)-2,5-diisopropylphospholano)benzene tetrafluoroborate; DuPhos Rhodium(I) Catalyst; [Rh((S,S)-Me-DuPhos)(COD)]BF4; (S,S)-Me-DuPhos Rh(COD)BF4; Chiral Rhodium DuPhos Complex; Asymmetric Hydrogenation Catalyst Rh-DuPhos; (1,5-cyclooctadiene)rhodium(I) (2S,5S)-1,2-bis(2,5-diisopropylphospholano)benzene tetrafluoroborate
EINECS	Contact for details

Quality Control

Our 1,2-Bis((2S,5S)-2,5-Diisopropylphospholano)Benzene(Cyclooctadiene)Rhodium(I) Tetrafluoroborate, 97% is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure identity, purity, and enantiomeric excess meet the specified standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a dry, cool place. This compound is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or elevated temperatures should be avoided to maintain catalytic activity and purity.

Specification

Item	Specification
Appearance	Orange to red-brown crystalline powder or solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Rhodium Content	Contact for details
Solubility	Soluble in dichloromethane, acetone; slightly soluble in toluene

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.