Description

3-Iodo-6-(Trifluoromethyl) (1H)Indazole is a high-value, multi-functional heterocyclic building block characterized by its indazole core substituted with iodine and a trifluoromethyl group. This unique structure makes it a critical intermediate for the synthesis of advanced pharmaceutical compounds and agrochemicals, particularly those targeting specific biological pathways. It is primarily utilized by research institutions and industrial R&D departments in the life sciences sector for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), especially in oncology, neurology, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Serves as a building block for creating new generations of herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Used in the synthesis of specialty chemicals and advanced materials, including organic light-emitting diodes (OLEDs) and liquid crystals.
• Chemical Biology & Proteomics: Employed as a molecular probe or tag in biochemical assays and for studying protein-ligand interactions due to its distinct structural motifs.
• Cross-Coupling Reactions: The iodine substituent makes it an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to create complex molecular architectures.

Basic Information

Product Name	3-Iodo-6-(Trifluoromethyl) (1H)Indazole
CAS No.	1000341-27-4
Molecular Formula	C8H4F3IN2
Molecular Weight	312.03 g/mol
Synonyms	3-Iodo-6-(trifluoromethyl)-1H-indazole; 6-(Trifluoromethyl)-1H-indazole-3-iodide; 1H-Indazole, 3-iodo-6-(trifluoromethyl)-; 3-Iodo-6-trifluoromethylindazole; 3-Iodo-6-trifluoromethyl-1H-indazole; 1000341-27-4; AI3-63535
EINECS	Contact for details

Quality Control

Our 3-Iodo-6-(Trifluoromethyl) (1H)Indazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality ensures reliable performance in your most sensitive synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.