Description

1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 5-Chloro-6-Methyl- is a high-purity heterocyclic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its unique fused pyrrolopyridine scaffold, which is a privileged structure in medicinal chemistry for designing bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries who require sophisticated intermediates for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Agrochemical Development: Serves as a building block for creating new herbicides, fungicides, and insecticides with novel modes of action.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and protein functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring complex heterocyclic chemistry.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 5-Chloro-6-Methyl-
CAS No.	1000340-12-4
Molecular Formula	C9H7ClN2O2
Molecular Weight	210.62 g/mol
Synonyms	5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid; 5-Chloro-6-methyl-1H-pyrrolo[2,3-b]pyridine-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-3-Carboxylic Acid, 5-Chloro-6-Methyl- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our commitment to quality supports compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and strong acids. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.