Description

Ethyl 2-Piperidin-1-Yl-4-(Trifluoromethyl)-1,3-Thiazole-5-Carboxylate is a high-value, multifunctional heterocyclic building block featuring a thiazole core substituted with piperidine and trifluoromethyl groups. This compound is engineered to serve as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its unique structure imparts desirable biological and physicochemical properties. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing new therapeutic and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and biological activity.
• Chemical Biology Research: Serves as a versatile scaffold for constructing molecular probes and libraries in drug discovery and mechanism-of-action studies.
• Material Science Precursor: Potential use in the synthesis of specialty polymers or organic electronic materials due to its complex heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: An essential building block for custom chemical synthesis services catering to the needs of biotechnology and pharmaceutical clients.

Basic Information

Product Name	Ethyl 2-Piperidin-1-Yl-4-(Trifluoromethyl)-1,3-Thiazole-5-Carboxylate
CAS No.	1000339-76-3
Molecular Formula	C12H15F3N2O2S
Molecular Weight	308.32 g/mol
Synonyms	Ethyl 2-(1-piperidinyl)-4-(trifluoromethyl)-1,3-thiazole-5-carboxylate; 5-Carbethoxy-2-piperidino-4-trifluoromethylthiazole; 1,3-Thiazole-5-carboxylic acid, 2-(1-piperidinyl)-4-(trifluoromethyl)-, ethyl ester; 2-Piperidin-1-yl-4-trifluoromethyl-thiazole-5-carboxylic acid ethyl ester; Ethyl 2-piperidino-4-(trifluoromethyl)thiazole-5-carboxylate; CAS 1000339-76-3
EINECS	Contact for details

Quality Control

Our Ethyl 2-Piperidin-1-Yl-4-(Trifluoromethyl)-1,3-Thiazole-5-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.