Description

3-Methyl-5-(Trifluoromethoxy)Phenylacetic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethoxy-substituted aromatic structure. This compound is valued for its role in modulating the physicochemical and metabolic properties of target molecules, making it a critical building block in modern medicinal chemistry. It is primarily sought after by R&D and process development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized monomers for specialty polymers with tailored thermal and chemical resistance properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	3-Methyl-5-(Trifluoromethoxy)Phenylacetic Acid
CAS No.	1000339-57-0
Molecular Formula	C10H9F3O3
Molecular Weight	234.17 g/mol
Synonyms	[2-(3-Methyl-5-(trifluoromethoxy)phenyl)]acetic acid; 3-Methyl-5-(trifluoromethoxy)benzeneacetic acid; α-(3-Methyl-5-(trifluoromethoxy)phenyl)acetic acid; 2-(3-Methyl-5-(trifluoromethoxyphenyl)acetic acid; (3-Methyl-5-(trifluoromethoxy)phenyl)acetic acid
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-(Trifluoromethoxy)Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with client specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. The product is light-sensitive and should be stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.