Description

(1S,2S,5R,6S,7S)-6,8,8-Trimethyl-3-Azatricyclo[5.1.1.02,5]Nonan-4-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique and complex tricyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drugs, including potential candidates for central nervous system (CNS) and anti-inflammatory applications.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex, high-value active pharmaceutical ingredients (APIs).
• Drug Discovery & Development: Used in medicinal chemistry research for creating novel drug candidates, especially in CNS and anti-inflammatory research pipelines.
• Asymmetric Synthesis: Serves as a valuable precursor in stereoselective synthesis due to its defined (1S,2S,5R,6S,7S) configuration.
• Chemical Research: Employed in academic and industrial R&D for studying structure-activity relationships (SAR) and developing new synthetic methodologies.
• Fine Chemical Production: Integral in the multi-step synthesis of specialty fine chemicals and complex organic molecules.

Basic Information

Product Name	(1S,2S,5R,6S,7S)-6,8,8-Trimethyl-3-Azatricyclo[5.1.1.02,5]Nonan-4-One
CAS No.	1000304-40-4
Molecular Formula	C11H17NO
Molecular Weight	179.26 g/mol
Synonyms	6,8,8-Trimethyl-3-azatricyclo[5.1.1.02,5]nonan-4-one; (1S,2S,5R,6S,7S)-6,8,8-Trimethyl-3-azatricyclo[5.1.1.0²,⁵]nonan-4-one; 3-Azatricyclo[5.1.1.02,5]nonan-4-one, 6,8,8-trimethyl-, (1S,2S,5R,6S,7S)-; Tricyclic lactam intermediate
EINECS	Contact for details

Quality Control

Our (1S,2S,5R,6S,7S)-6,8,8-Trimethyl-3-Azatricyclo[5.1.1.02,5]Nonan-4-One is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the exacting standards required for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided for each lot to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.