Description

3-Chloro-2-Fluoro-5-Nitrobenzoic Acid is a high-purity, multi-functional aromatic building block of significant importance in advanced organic synthesis. Its unique substitution pattern makes it a critical intermediate for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for research and development chemists and process engineers working on active pharmaceutical ingredients (APIs), crop protection agents, and specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting specific enzyme pathways where the chloro-fluoro-nitro substitution pattern is crucial for bioactivity.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, leveraging its aromatic structure for effective active ingredient design.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of organic electronic materials, liquid crystals, and polymers where its specific functional groups can modify material properties.
• Chemical Biology Probes: Useful for synthesizing labeled compounds and molecular probes for studying biological mechanisms and diagnostics.
• Custom Synthesis and Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	3-Chloro-2-Fluoro-5-Nitrobenzoic Acid
CAS No.	1000162-34-4
Molecular Formula	C7H3ClFNO4
Molecular Weight	219.55 g/mol
Synonyms	2-Fluoro-3-chloro-5-nitrobenzoic acid; 5-Nitro-3-chloro-2-fluorobenzoic acid; Benzoic acid, 3-chloro-2-fluoro-5-nitro-; 3-Chloro-2-fluoro-5-nitro-benzoic acid; 1000162-34-4; 3-Chloro-2-fluoro-5-nitrobenzoic acid (CAS 1000162-34-4)
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluoro-5-Nitrobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets the highest standards of purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.