Description

4-(4-Bromo-2-Fluorophenylsulfonyl)Morpholine is a high-purity, advanced pharmaceutical intermediate characterized by its sulfonyl morpholine and halogenated phenyl structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce specific halogenated aryl-sulfonamide motifs into target molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of potential drug candidates, particularly in kinase inhibitor and protease inhibitor research.
• Medicinal Chemistry R&D: Used in structure-activity relationship (SAR) studies to explore new chemical entities with therapeutic potential.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides and fungicides containing sulfonamide functional groups.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique electronic or surface properties.

Basic Information

Product Name	4-(4-Bromo-2-Fluorophenylsulfonyl)Morpholine
CAS No.	1000068-42-7
Molecular Formula	C10H11BrFNO3S
Molecular Weight	324.17 g/mol
Synonyms	4-[(4-Bromo-2-fluorophenyl)sulfonyl]morpholine; Morpholine, 4-[(4-bromo-2-fluorophenyl)sulfonyl]-; 4-(4-Bromo-2-fluorobenzene-1-sulfonyl)morpholine; 4-(4-Bromo-2-fluorophenylsulfonyl)morpholine; 1000068-42-7
EINECS	Contact for details

Quality Control

Our production of 4-(4-Bromo-2-Fluorophenylsulfonyl)Morpholine adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR, MS) to confirm identity and quantify purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality system is designed to support cGMP compliance for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong bases and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.