Description

8-Methoxy-2-(Trifluoromethyl)Quinoline-5-Carboxylic Acid is a high-purity, multifunctional quinoline derivative that serves as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in its unique molecular scaffold, which combines a methoxy group and a trifluoromethyl group on the quinoline core, making it an essential building block for creating complex molecules with tailored properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by fine chemical manufacturers producing specialty materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly for targets requiring the quinoline pharmacophore.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides where the trifluoromethyl group enhances biological activity and metabolic stability.
• Material Science: Serves as a building block for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Synthesis: Acts as a versatile intermediate for further functionalization, enabling the creation of complex libraries for high-throughput screening.
• Ligand & Catalyst Development: Utilized in the preparation of specialized ligands for catalysis in asymmetric synthesis.
• Fluorescent Probe Synthesis: The quinoline core makes it suitable for developing dyes and molecular probes for biochemical sensing and imaging.

Basic Information

Product Name	8-Methoxy-2-(Trifluoromethyl)Quinoline-5-Carboxylic Acid
CAS No.	199872-29-2
Molecular Formula	C₁₂H₈F₃NO₃
Molecular Weight	271.19 g/mol
Synonyms	8-Methoxy-2-(trifluoromethyl)-5-quinolinecarboxylic acid; 5-Quinolinecarboxylic acid, 8-methoxy-2-(trifluoromethyl)-; 2-Trifluoromethyl-8-methoxy-quinoline-5-carboxylic acid; 199872-29-2; 8-Methoxy-2-trifluoromethylquinoline-5-carboxylic Acid; 8-Methoxy-2-(trifluoromethyl)quinoline-5-carboxylate
EINECS	Contact for details

Quality Control

Our 8-Methoxy-2-(Trifluoromethyl)Quinoline-5-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.