Description

4-(Trifluoromethoxy)Cinnamic Acid is a high-value fluorinated organic building block characterized by its cinnamic acid backbone and trifluoromethoxy substituent. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced synthesis. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in areas requiring enhanced bioavailability and receptor binding affinity.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group can improve biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor in the development of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Chemical Research & Development: A versatile reagent for academic and industrial R&D in medicinal chemistry and material science.
• Fluorinated Polymer Modification: Can be utilized to introduce fluorinated segments into polymers, altering their surface properties and chemical resistance.

Basic Information

Product Name	4-(Trifluoromethoxy)Cinnamic Acid
CAS No.	199679-35-1
Molecular Formula	C10H7F3O3
Molecular Weight	232.16 g/mol
Synonyms	(E)-3-[4-(Trifluoromethoxy)phenyl]acrylic acid; 4-(Trifluoromethoxy)benzeneacrylic acid; trans-4-(Trifluoromethoxy)cinnamic acid; α,4-Bis(trifluoromethoxy)benzenepropanoic acid (related); p-(Trifluoromethoxy)cinnamic acid; 3-(4-Trifluoromethoxyphenyl)-2-propenoic acid
EINECS	Contact for details

Quality Control

Our 4-(Trifluoromethoxy)Cinnamic Acid is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the stringent requirements of our global clientele. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.