Description

4-(Pyrimidin-2-Yl)Benzoic Acid is a high-purity organic building block featuring a benzoic acid moiety linked to a pyrimidine heterocycle. This bifunctional structure makes it a critical intermediate for synthesizing advanced pharmaceutical compounds and functional materials. It is primarily utilized by research institutions and industrial manufacturers in the life sciences and specialty chemical sectors for developing new active ingredients and ligands.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides that require specific heterocyclic architectures for activity.
• Ligand & Chelator Development: Serves as a precursor for constructing complex ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and polymers requiring precise molecular engineering.
• Bioconjugation & Probe Synthesis: The carboxylic acid group allows for coupling to biomolecules or other entities to create diagnostic probes or chemical tools.

Basic Information

Product Name	4-(Pyrimidin-2-Yl)Benzoic Acid
CAS No.	199678-12-1
Molecular Formula	C11H8N2O2
Molecular Weight	200.20 g/mol
Synonyms	2-(4-Carboxyphenyl)pyrimidine; 4-(2-Pyrimidinyl)benzoic Acid; Benzoic acid, 4-(2-pyrimidinyl)-; 4-Pyrimidin-2-yl-benzoic acid; 2-(4-Carboxy-phenyl)-pyrimidine; 4-(Pyrimidin-2-yl)benzoic acid; p-(2-Pyrimidyl)benzoic Acid
EINECS	Contact for details

Quality Control

Our 4-(Pyrimidin-2-Yl)Benzoic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for research and production. Certificates of Analysis (COA) documenting all specifications are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the original container tightly sealed to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.