Description

Benzoic Acid, 3-(Fluorosulfonyl)-4-Methoxy- is a specialized fluorosulfonyl-substituted benzoic acid derivative, serving as a high-value synthetic intermediate. Its unique structure, featuring both a fluorosulfonyl and a methoxy group on the aromatic ring, makes it a critical building block for constructing complex molecules in advanced research and development. This compound is primarily targeted at the pharmaceutical, agrochemical, and advanced materials industries, where it is used to introduce key functional groups for creating novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for sulfonamide-based drugs and molecules requiring a fluorosulfonyl moiety.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorosulfonyl group can enhance biological activity and stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent enzyme inhibitors due to the electrophilic fluorosulfonyl group.
• Organic Synthesis Building Block: A versatile reagent for introducing the -SO2F group into complex organic frameworks, enabling further derivatization to sulfonamides, sulfonic acids, or sulfonate esters.

Basic Information

Product Name	Benzoic Acid, 3-(Fluorosulfonyl)-4-Methoxy-
CAS No.	199461-16-0
Molecular Formula	C8H7FO5S
Molecular Weight	234.20 g/mol
Synonyms	4-Methoxy-3-(fluorosulfonyl)benzoic acid; 3-Fluorosulfonyl-4-methoxybenzoic acid; 3-(Fluorosulfonyl)-4-methoxybenzoic acid; Benzoic acid, 4-methoxy-3-sulfonyl fluoride; 4-Methoxy-3-sulfonylfluorobenzoic acid; 3-SO2F-4-MeO-benzoic acid; 3-(Fluorosulphonyl)-4-methoxybenzoic acid
EINECS	Contact for details

Quality Control

Our Benzoic Acid, 3-(Fluorosulfonyl)-4-Methoxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under dry conditions to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 96.0% (by titration)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.