Description

2-Azabicyclo[2.2.1]Hept-5-En-3-One, 2-(2-Methyl-1-Oxopropyl)- is a high-value, advanced pharmaceutical intermediate characterized by its unique bridged bicyclic structure. This compound is essential for the synthesis of complex molecules, serving as a key chiral building block in modern medicinal chemistry. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

This specialized intermediate is a critical precursor in the synthesis of a wide range of bioactive molecules. Its primary applications include:

• Pharmaceutical Synthesis: As a key chiral scaffold for the development of new drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Intermediates: Used in the production of advanced, high-performance pesticides and herbicides.
• Catalyst and Ligand Development: Serves as a precursor for sophisticated chiral ligands used in asymmetric catalysis.
• Academic and R&D Laboratories: A valuable tool for synthetic organic chemists exploring new reaction methodologies and complex natural product synthesis.
• Fine Chemical Production: Employed in the manufacture of other high-purity, complex specialty chemicals.

Basic Information

Product Name	2-Azabicyclo[2.2.1]Hept-5-En-3-One, 2-(2-Methyl-1-Oxopropyl)-
CAS No.	199395-78-3
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	2-(2-Methylpropanoyl)-2-azabicyclo[2.2.1]hept-5-en-3-one; 2-Isobutyryl-2-azabicyclo[2.2.1]hept-5-en-3-one; 3-Oxo-2-(2-methyl-1-oxopropyl)-2-azabicyclo[2.2.1]hept-5-ene; N-Isobutyryl-5-norbornene-2-carboxamide (derived structure); Bridged lactam intermediate; 2-Azabicyclo[2.2.1]hept-5-ene-3-one, 2-(2-methyl-1-oxopropyl)-
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for this high-purity intermediate. Production adheres to current industry best practices, and each batch is analyzed to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, chiral purity, and impurity profiles are provided with every shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider maintaining the product under an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Related Substances (HPLC)	Any single impurity ≤ 0.5%; Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.