Description

1-Bromocyclopropanecarboxamide is a high-value brominated cyclopropane derivative, serving as a versatile and critical building block in advanced organic synthesis. Its unique strained-ring structure functionalized with both bromine and an amide group makes it an indispensable reagent for constructing complex molecular architectures. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications in medicinal chemistry and catalyst design.

Application

• Pharmaceutical Intermediate: A key synthon for the preparation of novel active pharmaceutical ingredients (APIs), particularly in the development of enzyme inhibitors and receptor modulators.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that leverage the cyclopropane motif for biological activity.
• Material Science Research: Employed as a monomer or cross-linking agent in the synthesis of specialized polymers with unique thermal or mechanical properties.
• Medicinal Chemistry: Facilitates structure-activity relationship (SAR) studies and the exploration of chemical space through cyclopropanation and further functionalization.
• Chemical Biology Probes: Acts as a precursor for labeling reagents or activity-based probes used to study biological pathways and protein function.
• Catalyst and Ligand Development: Serves as a starting material for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	1-Bromocyclopropanecarboxamide
CAS No.	198758-97-3
Molecular Formula	C4H6BrNO
Molecular Weight	164.00 g/mol
Synonyms	Cyclopropanecarboxamide, 1-bromo-; 1-Bromo-cyclopropanecarboxylic acid amide; 1-Bromocyclopropanecarboxylic acid amide; 1-Bromo-1-carbamoylcyclopropane; (1-Bromocyclopropyl)carboxamide; 1-Bromo-cyclopropanecarboxamide; 198758-97-3; Bromocyclopropanecarboxamide
EINECS	Contact for details

Quality Control

Our 1-Bromocyclopropanecarboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring reliability for your most critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.