Description

Ethyl (E)-3-(4-Aminophenyl)Prop-2-Enoate CAS NO 198195-25-4 is a high-purity, synthetic organic compound featuring a conjugated enoate ester structure with a primary aromatic amine group. This unique molecular architecture makes it a versatile and critical building block in advanced organic synthesis, particularly for creating complex heterocycles and functionalized intermediates. It is primarily sought after by pharmaceutical research and fine chemical manufacturers for the development of active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Fine Chemical Synthesis: Serves as a crucial building block for creating complex molecules like chalcones, stilbenes, and other pharmacologically active scaffolds.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and plant growth regulators due to its reactive amine and ester functionalities.
• Material Science: Potential monomer or cross-linking agent in the research of specialty polymers and advanced organic materials.
• Dye and Pigment Industry: Acts as an intermediate for synthesizing azo dyes and other colorants, leveraging its aromatic amine group.
• Academic & R&D: Employed in university and corporate research laboratories for methodological studies in organic chemistry and medicinal chemistry.

Basic Information

Product Name	Ethyl (E)-3-(4-Aminophenyl)Prop-2-Enoate
CAS No.	198195-25-4
Molecular Formula	C11H13NO2
Molecular Weight	191.23 g/mol
Synonyms	(E)-Ethyl 3-(4-aminophenyl)acrylate; Ethyl (E)-3-(4-aminophenyl)acrylate; 4-Aminocinnamic acid ethyl ester; (E)-Ethyl 4-aminocinnamate; Ethyl p-aminocinnamate; Ethyl trans-4-aminocinnamate; p-Aminocinnamic Acid Ethyl Ester; Ethyl (E)-3-(4-aminophenyl)-2-propenoate
EINECS	Contact for details

Quality Control

Our Ethyl (E)-3-(4-Aminophenyl)Prop-2-Enoate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent oxidation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.