Description

4-Chloro-5H-Indeno[1,2-D]Pyrimidine is a high-value, heterocyclic organic compound featuring a fused indene and pyrimidine ring system with a reactive chlorine substituent. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily utilized by R&D scientists and process chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active compounds. The compound's structure is pivotal for developing molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Synthesis: Acts as an intermediate in the development of new pesticides and herbicides, leveraging its heterocyclic framework.
• Chemical Biology Probe Development: Employed in the design and creation of molecular probes to study biological pathways and target validation.
• Organic Electronic Materials Research: Investigated as a potential component in the development of novel organic semiconductors due to its conjugated system.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specialized heterocycles.

Basic Information

Product Name	4-Chloro-5H-Indeno[1,2-D]Pyrimidine
CAS No.	197861-27-1
Molecular Formula	C11H7ClN2
Molecular Weight	202.64 g/mol
Synonyms	4-Chloro-5H-indeno[1,2-d]pyrimidine; 5H-Indeno[1,2-d]pyrimidine, 4-chloro-; 4-Chloroindeno[1,2-d]pyrimidine; 4-Chloro-5H-indeno[1,2-d]pyrimidin; Indeno[1,2-d]pyrimidine, 4-chloro-5H-; 197861-27-1; 4-Cl-5H-Indeno[1,2-d]pyrimidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-5H-Indeno[1,2-D]Pyrimidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the high standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.