Description

8-Azabicyclo[3.2.1]Octan-2-One,6,8-Dimethyl-,(1R,5R,6R)-Rel-(9Ci) is a high-purity, stereochemically defined bicyclic lactam building block of significant interest in advanced organic synthesis. Its rigid, three-dimensional scaffold makes it a valuable intermediate for constructing complex molecular architectures with precise spatial orientation. This compound is primarily sought after by pharmaceutical research and development organizations for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in areas requiring sophisticated chiral templates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, including central nervous system (CNS) drugs and alkaloid-based pharmaceuticals.
• Asymmetric Synthesis: Serves as a sophisticated building block in stereoselective reactions to introduce complex, constrained ring systems into target molecules.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore novel chemical space and improve drug-like properties.
• Process Chemistry Development: Employed in the scale-up and route scouting for the commercial production of chiral APIs.
• Academic & Institutional Research: Utilized in synthetic methodology development and the total synthesis of natural products with complex polycyclic frameworks.
• Fine Chemical Production: Acts as a precursor for other high-value, specialty chemicals requiring its unique bicyclic lactam structure.

Basic Information

Product Name	8-Azabicyclo[3.2.1]Octan-2-One,6,8-Dimethyl-,(1R,5R,6R)-Rel-(9Ci)
CAS No.	197588-50-4
Molecular Formula	C9H15NO
Molecular Weight	153.22 g/mol
Synonyms	(1R,5R,6R)-6,8-Dimethyl-8-azabicyclo[3.2.1]octan-2-one; rel-(1R,5R,6R)-6,8-Dimethyl-8-azabicyclo[3.2.1]octan-2-one; 6,8-Dimethyl-8-azabicyclo[3.2.1]octan-2-one, (1R,5R,6R)-rel-; Bicyclic Lactam Derivative; 8-Azabicyclo[3.2.1]octan-2-one, 6,8-dimethyl-, (1R,5R,6R)-rel-; 197588-50-4; (rel)-(1R,5R,6R)-6,8-Dimethyl-8-azabicyclo[3.2.1]octan-2-one
EINECS	Contact for details

Quality Control

Our 8-Azabicyclo[3.2.1]Octan-2-One,6,8-Dimethyl-,(1R,5R,6R)-Rel-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the exacting standards required for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.