Description

4-(2-Amino-3-Chlorophenyl)Benzoic Acid is a high-purity, bifunctional aromatic compound that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both an amino and a carboxylic acid group on a chlorinated biphenyl core, makes it an exceptionally versatile intermediate for creating complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to develop new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, where its chlorinated aromatic structure contributes to biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Functions as a monomer or chain modifier in the production of high-performance polymers, such as polyamides and polyimides, due to its dual functional groups.
• Dye and Pigment Manufacturing: Employed in the synthesis of complex organic dyes and pigments, where its amino group allows for diazotization and further coupling reactions.
• Academic and Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cross-coupling reactions and heterocycle formation.

Basic Information

Product Name	4-(2-Amino-3-Chlorophenyl)Benzoic Acid
CAS No.	197450-30-9
Molecular Formula	C13H10ClNO2
Molecular Weight	247.68 g/mol
Synonyms	2'-Amino-3'-chloro-[1,1'-biphenyl]-4-carboxylic acid; 3-Chloro-2-aminobiphenyl-4'-carboxylic Acid; 4-(2-Amino-3-chlorophenyl)benzoic acid; [1,1'-Biphenyl]-4-carboxylic acid, 2'-amino-3'-chloro-; 2-Amino-3-chlorobiphenyl-4'-carboxylic Acid; 3-Chloro-2-aminodiphenyl-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Our production of 4-(2-Amino-3-Chlorophenyl)Benzoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. We provide full traceability and a Certificate of Analysis (COA) with every shipment, detailing all critical specifications. Our quality systems are designed to support cGMP (current Good Manufacturing Practice) requirements for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.