Description

6-Bromo-1,4,4-Trimethyl-1,2,3,4-Tetrahydroquinoline is a specialized brominated tetrahydroquinoline derivative, a key synthetic intermediate in advanced organic chemistry. Its value lies in its unique halogenated quinoline scaffold, which is crucial for constructing complex molecules with potential biological activity. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and for use in material science research.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing antimicrobial properties.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the bromine atom and quinoline structure can be leveraged for bioactivity.
• Material Science Precursor: Acts as a starting material for the synthesis of functionalized organic compounds used in advanced materials, such as organic semiconductors or ligands for catalysis.
• Chemical Synthesis Reagent: Employed in academic and industrial R&D labs for method development, structure-activity relationship (SAR) studies, and the exploration of new heterocyclic chemistry.
• Ligand and Catalyst Development: The nitrogen-containing quinoline core can be modified to create novel ligands for transition metal catalysts used in cross-coupling and other synthetic transformations.

Basic Information

Product Name	6-Bromo-1,4,4-Trimethyl-1,2,3,4-Tetrahydroquinoline
CAS No.	197379-70-7
Molecular Formula	C₁₂H₁₆BrN
Molecular Weight	254.17 g/mol
Synonyms	6-Bromo-1,4,4-trimethyl-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-6-bromo-1,4,4-trimethylquinoline; Quinoline, 6-bromo-1,2,3,4-tetrahydro-1,4,4-trimethyl-; 6-Bromo-1,4,4-trimethyl-3,4-dihydro-1H-quinoline; 197379-70-7
EINECS	Contact for details

Quality Control

Our 6-Bromo-1,4,4-Trimethyl-1,2,3,4-Tetrahydroquinoline is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.