Description

C12 Dihydroceramide (D18:0/12:0) CAS NO 197302-96-8 is a high-purity, synthetic dihydroceramide featuring a sphingosine base (D18:0) and a lauric acid (C12:0) chain. This compound serves as a critical intermediate and reference standard in lipid metabolism research and advanced cosmetic formulations. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and personal care industries who require precise, well-characterized sphingolipids for product development and analytical applications.

Application

• Biomedical Research: Used as a key intermediate in studying the biosynthesis and metabolic pathways of ceramides and sphingolipids, crucial for understanding cell signaling, apoptosis, and skin barrier function.
• Cosmetic & Skincare Actives: Incorporated into premium anti-aging and barrier-repair formulations to mimic natural skin lipids, enhancing moisturization and improving skin texture.
• Analytical Reference Standard: Serves as a high-purity calibrant and standard in HPLC, LC-MS, and other analytical methods for quantifying ceramides in complex biological or cosmetic matrices.
• Lipidomics & Metabolomics: A vital component in targeted lipid profiling kits and research studies aiming to map lipid species and their roles in health and disease.
• Pharmaceutical Development: Investigated as a potential precursor or active pharmaceutical ingredient (API) in therapies targeting dermatological conditions or metabolic disorders.
• Cell Culture & In Vitro Studies: Used to supplement media in specialized cell culture applications to study lipid-mediated cellular processes and membrane dynamics.

Basic Information

Product Name	C12 Dihydroceramide (D18:0/12:0)
CAS No.	197302-96-8
Molecular Formula	C30H61NO3
Molecular Weight	483.82 g/mol
Synonyms	N-[(2S,3R)-1,3-Dihydroxyoctadecan-2-yl]dodecanamide; N-Lauroyl-D-erythro-sphinganine; D-erythro-C12-Dihydroceramide; Dihydro-N-lauroyl-D-erythro-sphingosine; Cer(d18:0/12:0); Dihydroceramide (d18:0/12:0); N-Dodecanoylsphinganine; Lauroyl dihydroceramide
EINECS	Contact for details

Quality Control

Our C12 Dihydroceramide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing including HPLC for purity, MS for structural confirmation, and specific tests for residual solvents and moisture to ensure it meets the high standards required for research and formulation. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistency for our global customers.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area%)	≥ 98.0%
Melting Point	Contact for details
Specific Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.