Description

H-p-Amino-D-Phe-Oh Hcl is a high-purity, non-natural amino acid derivative, specifically the D-isomer of para-aminophenylalanine hydrochloride. This compound serves as a critical chiral building block and intermediate in advanced organic synthesis, enabling the creation of complex molecules with precise stereochemistry. It is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing peptide-based therapeutics, diagnostic agents, and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for peptide drugs and hormone analogs.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate the D-configuration of para-aminophenylalanine, influencing peptide stability and bioactivity.
• Research & Development: Vital building block in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new chemical libraries.
• Diagnostic Agent Production: Intermediate in the manufacture of contrast agents and radiopharmaceuticals for imaging applications.
• Bioconjugation: The aromatic amine group facilitates site-specific labeling and conjugation of biomolecules for drug delivery systems.

Basic Information

Product Name	H-p-Amino-D-Phe-Oh Hcl
CAS No.	196408-63-6
Molecular Formula	C9H13ClN2O2
Molecular Weight	216.66 g/mol
Synonyms	(R)-2-Amino-3-(4-aminophenyl)propanoic acid hydrochloride; D-4-Aminophenylalanine hydrochloride; D-p-Amino-Phe-OH·HCl; H-D-Phe(4-NH2)-OH·HCl; D-Phenylalanine, 4-amino-, hydrochloride (1:1); (2R)-2-Azaniumyl-3-(4-aminophenyl)propanoate chloride
EINECS	Contact for details

Quality Control

Our H-p-Amino-D-Phe-Oh Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed HPLC, NMR, and optical rotation data are provided to guarantee consistent quality and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (D-isomer)
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm
Optical Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.