Description

4-(2-Cyano-3-Fluorophenyl)Benzoic Acid is a high-purity, multi-functional organic building block featuring both a benzoic acid and a fluorinated benzonitrile moiety. This compound is valued for its role as a critical intermediate in the synthesis of advanced pharmaceutical compounds and specialty materials. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and pesticides, leveraging the fluorinated aromatic structure.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated and cyano-substituted aromatic cores used in electronic display technologies.
• Polymer Modification: Employed to introduce fluorinated phenyl groups into polymer chains to alter thermal stability, solubility, and surface properties.
• Organic Synthesis Reagent: Utilized in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and as a precursor for further functional group transformations in complex organic synthesis.
• Chemical Research & Development: A versatile scaffold for academic and industrial research into new chemical entities and material properties.

Basic Information

Product Name	4-(2-Cyano-3-Fluorophenyl)Benzoic Acid
CAS No.	195457-73-9
Molecular Formula	C14H8FNO2
Molecular Weight	241.22 g/mol
Synonyms	[4-(2-Cyano-3-fluorophenyl)phenyl]formic acid; 4'-(2-Cyano-3-fluoro)benzophenone-4-carboxylic acid; 3-Fluoro-2-cyanobiphenyl-4-carboxylic acid; 4-(2-Cyano-3-fluorophenyl)benzoic acid; 2-Cyano-3-fluoro-4'-carboxybiphenyl; Biphenyl-4-carboxylic acid, 2-cyano-3-fluoro-; 195457-73-9; 4-(2-Cyano-3-fluorophenyl)benzoic acid
EINECS	Contact for details

Quality Control

Our production of 4-(2-Cyano-3-Fluorophenyl)Benzoic Acid adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and MS for comprehensive characterization. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.