Description

6-Bromo-n-(3-Chloro-4-Fluorophenyl)Quinazolin-4-Amine is a high-purity, advanced pharmaceutical intermediate belonging to the quinazoline class of heterocyclic compounds. This compound matters as a critical building block in the synthesis of targeted therapeutic agents, offering precise molecular functionality for research and development. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors for oncology and inflammatory disease research.
• Biochemical Research: Used as a reference standard or a molecular scaffold in structure-activity relationship (SAR) studies.
• Organic Synthesis Building Block: Serves as a versatile substrate for further functionalization via cross-coupling reactions, leveraging the bromo and amine groups.
• Agrochemical Development: Potential application in the research and synthesis of new active ingredients for crop protection.
• Material Science Research: Investigated for the development of organic electronic materials due to the quinazoline core's electronic properties.

Basic Information

Product Name	6-Bromo-n-(3-Chloro-4-Fluorophenyl)Quinazolin-4-Amine
CAS No.	195457-61-5
Molecular Formula	C14H8BrClFN3
Molecular Weight	352.59 g/mol
Synonyms	6-Bromo-N-(3-chloro-4-fluorophenyl)quinazolin-4-amine; 4-Quinazolinamine, 6-bromo-N-(3-chloro-4-fluorophenyl)-; 6-Bromo-4-((3-chloro-4-fluorophenyl)amino)quinazoline; 195457-61-5; BRN 11817647; N-(3-Chloro-4-fluorophenyl)-6-bromoquinazolin-4-amine; 6-Bromo-N-(3-chloro-4-fluorophenyl)-4-quinazolinamine
EINECS	Contact for details

Quality Control

Our 6-Bromo-n-(3-Chloro-4-Fluorophenyl)Quinazolin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.