Description

n-(2,2,2-Trifluoroethyl)-2-Propanamine Hydrochloride is a specialized fluorinated amine hydrochloride salt, a key building block in advanced organic synthesis. Its trifluoroethyl group imparts unique electronic and lipophilic properties, making it valuable for modifying the pharmacokinetic profiles of target molecules. This high-purity intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical sectors for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing candidates for central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating novel ligands and organocatalysts used in asymmetric synthesis and transition metal catalysis.
• Material Science Research: Employed in the development of specialty polymers, coatings, and liquid crystals where fluorinated amines modify surface properties and stability.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes and drug-target interactions.

Basic Information

Product Name	n-(2,2,2-Trifluoroethyl)-2-Propanamine Hydrochloride
CAS No.	195447-36-0
Molecular Formula	C5H11ClF3N
Molecular Weight	177.60 g/mol
Synonyms	1,1,1-Trifluoro-N-isopropylethanamine Hydrochloride; N-Isopropyl-2,2,2-trifluoroethylamine Hydrochloride; 2-Propanamine, N-(2,2,2-trifluoroethyl)-, hydrochloride; 2,2,2-Trifluoro-N-isopropylethylamine HCl; TFIPA·HCl; N-(2,2,2-Trifluoroethyl)isopropylamine Hydrochloride
EINECS	Contact for details

Quality Control

Our n-(2,2,2-Trifluoroethyl)-2-Propanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and process chemistry. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.