Description

2-(1-Trityl-1H-Imidazol-4-Yl)-Ethylamine Hydrate is a specialized, protected amine derivative of imidazole, serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of pharmaceuticals and bioactive molecules, particularly where selective amine protection is required. It is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing imidazole and ethylamine pharmacophores.
• Peptide Mimetics & Drug Discovery: Used in medicinal chemistry to create novel peptide analogs and small molecule libraries for screening against biological targets.
• Agrochemical Synthesis: Serves as a building block for developing new fungicides, herbicides, and plant growth regulators.
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for metal catalysis and organocatalysts.
• Bioconjugation & Linker Chemistry: The protected amine group is useful for creating cleavable linkers in antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Academic & Industrial R&D: A valuable reagent for method development and exploring new synthetic pathways in organic chemistry laboratories.

Basic Information

Product Name	2-(1-Trityl-1H-Imidazol-4-Yl)-Ethylamine Hydrate
CAS No.	195053-92-0
Molecular Formula	C24H23N3O (anhydrous basis)
Molecular Weight	369.46 g/mol (anhydrous basis)
Synonyms	2-(1-Trityl-1H-imidazol-4-yl)ethanamine hydrate; 4-(2-Aminoethyl)-1-trityl-1H-imidazole hydrate; 1-Trityl-4-(2-aminoethyl)imidazole hydrate; 2-(1-Triphenylmethyl-1H-imidazol-4-yl)ethylamine hydrate; N-Trityl-4-(2-aminoethyl)imidazole hydrate; 195053-92-0; 2-(1-Tritylimidazol-4-yl)ethylamine hydrate
EINECS	Contact for details

Quality Control

Our 2-(1-Trityl-1H-Imidazol-4-Yl)-Ethylamine Hydrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and KF titration for water content to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccant packs or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 3.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.