Description

3-Quinolinecarboxylic Acid,7-Bromo-1-Cyclopropyl-1,4-Dihydro-8-Methyl-4-Oxo-, Ethyl Ester is a high-purity, synthetically valuable quinoline derivative. This compound serves as a critical pharmaceutical intermediate and research chemical for the development of novel active ingredients. It is primarily sought by R&D chemists and process development teams in the pharmaceutical and agrochemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential antibacterial and anticancer agents targeting DNA gyrase and topoisomerase IV.
• Agrochemical Research: Used in developing novel fungicides and bactericides due to its quinoline core structure.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization via its ester and halogen groups for custom compound libraries.
• Academic & Institutional Research: Employed in medicinal chemistry programs to study structure-activity relationships (SAR) of quinolone derivatives.
• Process Chemistry Development: Used for scaling up and optimizing synthetic routes for advanced pharmaceutical ingredients (APIs).

Basic Information

Product Name	3-Quinolinecarboxylic Acid,7-Bromo-1-Cyclopropyl-1,4-Dihydro-8-Methyl-4-Oxo-, Ethyl Ester
CAS No.	194805-04-4
Molecular Formula	C16H16BrNO3
Molecular Weight	350.21 g/mol
Synonyms	7-Bromo-1-cyclopropyl-1,4-dihydro-8-methyl-4-oxo-3-quinolinecarboxylic acid ethyl ester; Ethyl 7-bromo-1-cyclopropyl-8-methyl-4-oxo-1,4-dihydroquinoline-3-carboxylate; 1-Cyclopropyl-7-bromo-1,4-dihydro-8-methyl-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; ABT-492 Intermediate; Quinolone Derivative CAS 194805-04-4
EINECS	Contact for details

Quality Control

Every batch of our 3-Quinolinecarboxylic Acid,7-Bromo-1-Cyclopropyl-1,4-Dihydro-8-Methyl-4-Oxo-, Ethyl Ester is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical R&D and scale-up processes. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥97.0%
Related Substances (HPLC)	Total impurities ≤3.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.