Description

(S)-2-Amino-7-Hydroxytetralin Hydrobromide is a high-purity chiral intermediate and a key building block in organic synthesis. This compound is valued for its role in the research and development of active pharmaceutical ingredients (APIs), particularly those targeting neurological pathways. It is essential for pharmaceutical manufacturers, research institutions, and fine chemical companies engaged in the synthesis of complex molecules for therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of advanced pharmaceutical compounds, particularly for central nervous system (CNS) drug discovery and development.
• Dopamine Receptor Research: Used as a key ligand and reference standard in neurological research focused on dopamine receptor subtypes and related neurological pathways.
• Asymmetric Synthesis: Serves as a valuable chiral building block for constructing complex molecules with defined stereochemistry in medicinal chemistry.
• Reference Standard: Employed as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological mechanisms and protein-ligand interactions.
• Process Chemistry Development: Integral to scaling up synthetic routes for potential drug candidates during process research and optimization.

Basic Information

Product Name	(S)-2-Amino-7-Hydroxytetralin Hydrobromide
CAS No.	194785-79-0
Molecular Formula	C₁₀H₁₄BrNO
Molecular Weight	244.13 g/mol
Synonyms	(2S)-2-Amino-5,6,7,8-tetrahydro-2-naphthalenol hydrobromide; (S)-2-Amino-5,6,7,8-tetrahydro-2-naphthol HBr; (S)-2-Amino-7-hydroxytetralin HBr; (S)-2-Amino-5,6,7,8-tetrahydro-2-naphthol Hydrobromide; (S)-2-Amino-7-hydroxy-1,2,3,4-tetrahydronaphthalene Hydrobromide; (S)-A-77636 Hydrobromide; (S)-(-)-2-Amino-7-hydroxytetralin Hydrobromide
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-7-Hydroxytetralin Hydrobromide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert conditions or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.