Description

Ethyl α-Cyano-4-(1-Piperidinylcarbonyl)-2-Quinolineacetate is a sophisticated quinoline derivative ester, serving as a critical advanced intermediate in modern organic synthesis. Its molecular architecture, featuring a cyanoacetate group and a piperidine carbonyl moiety, makes it a versatile building block for constructing complex nitrogen-containing heterocycles. This compound is primarily utilized by research institutions and pharmaceutical development teams engaged in the creation of novel active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing kinase inhibitory activity.
• Organic Synthesis Building Block: Used in multi-step synthetic routes to construct complex quinoline-based scaffolds for material science and agrochemical research.
• Research & Development (R&D): Essential for medicinal chemistry programs in academic and industrial laboratories for structure-activity relationship (SAR) studies.
• Fine Chemical Production: Employed in the manufacture of high-value, low-volume specialty chemicals requiring specific quinoline frameworks.

Basic Information

Product Name	Ethyl α-Cyano-4-(1-Piperidinylcarbonyl)-2-Quinolineacetate
CAS No.	194713-20-7
Molecular Formula	C20H21N3O3
Molecular Weight	351.40 g/mol
Synonyms	Ethyl 2-Cyano-2-(4-[(piperidine-1-carbonyl)quinolin-2-yl])acetate; 2-Quinolineacetic acid, α-cyano-4-(1-piperidinylcarbonyl)-, ethyl ester; Ethyl α-cyano-4-(piperidine-1-carbonyl)quinoline-2-acetate; 194713-20-7; 4-(1-Piperidinylcarbonyl)-2-quinolineacetic acid α-cyano- ethyl ester; Ethyl (cyano){4-[(1-piperidinyl)carbonyl]-2-quinolinyl}acetate; UNII-9F6D8Q8V4R
EINECS	Contact for details

Quality Control

Our production of Ethyl α-Cyano-4-(1-Piperidinylcarbonyl)-2-Quinolineacetate adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to protect the compound from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.