Description

4-(4-Iodo-Phenyl)-4-Oxo-Butyric Acid is a high-purity iodinated aromatic ketone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile molecular scaffold with both a reactive carbonyl and a carboxylic acid functional group, enabling precise chemical modifications. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in developing advanced herbicides and plant growth regulators, leveraging its halogenated aromatic structure.
• Liquid Crystal & OLED Materials: Serves as a building block for iodinated aromatic cores in electronic and photonic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) to create complex biaryl structures.
• Peptide Mimetics & Conjugation: The carboxylic acid group facilitates coupling to amines, useful in creating peptide analogs or antibody-drug conjugate (ADC) linkers.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	4-(4-Iodo-Phenyl)-4-Oxo-Butyric Acid
CAS No.	194146-02-6
Molecular Formula	C10H9IO3
Molecular Weight	304.08 g/mol
Synonyms	4-(4-Iodophenyl)-4-oxobutanoic Acid; γ-Oxo-4-iodobenzenebutanoic Acid; 4-(p-Iodophenyl)-4-oxobutyric Acid; 4-Oxo-4-(4-iodophenyl)butyric Acid; 4-Iodophenyl Levulinate Acid; 194146-02-6; Butyric acid, 4-(4-iodophenyl)-4-oxo-
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Iodo-Phenyl)-4-Oxo-Butyric Acid is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Our standard quality commitment includes HPLC purity ≥97% (typical), with full characterization by NMR, IR, and MS. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.