Description

7-Oxa-2-Azaspiro[3.5]Nonane-2-Carboxylic Acid, 1-Oxo-, 1,1-Dimethylethyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a critical building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, including protease inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel active pharmaceutical ingredients (APIs) targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing spirocyclic compound libraries in drug discovery and lead optimization programs.
• Protease Inhibitor Development: Serves as a core structural element in the design and synthesis of potential protease inhibitor candidates.
• Chemical Biology: Employed in the synthesis of specialized probes and tool compounds for studying enzyme function and biological mechanisms.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes requiring this spirocyclic motif.

Basic Information

Product Name	7-Oxa-2-Azaspiro[3.5]Nonane-2-Carboxylic Acid, 1-Oxo-, 1,1-Dimethylethyl Ester
CAS No.	193023-02-8
Molecular Formula	C11H17NO4
Molecular Weight	227.26 g/mol
Synonyms	tert-Butyl 1-oxo-7-oxa-2-azaspiro[3.5]nonane-2-carboxylate; 2-(tert-Butoxycarbonyl)-7-oxa-2-azaspiro[3.5]nonan-1-one; Boc-7-Oxa-2-azaspiro[3.5]nonan-1-one; 1-Oxo-7-oxa-2-azaspiro[3.5]nonane-2-carboxylic Acid tert-Butyl Ester; 7-Oxa-2-azaspiro[3.5]nonane-1-one, 2-[(1,1-dimethylethoxy)carbonyl]-; 193023-02-8; Boc-Protected 7-Oxa-2-azaspiro[3.5]nonan-1-one
EINECS	Contact for details

Quality Control

Our production of 7-Oxa-2-Azaspiro[3.5]Nonane-2-Carboxylic Acid, 1-Oxo-, 1,1-Dimethylethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere if long-term storage is required to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.