Description

8-Fluoro-Chroman-4-Ylamine Hydrochloride is a high-purity fluorinated chroman derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in the strategic incorporation of fluorine and the chroman scaffold, which are pivotal for modulating the biological activity, metabolic stability, and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, cardiovascular diseases, and other therapeutic areas.
• Agrochemical Research: Building block for developing new-generation herbicides, fungicides, and insecticides where the chroman structure imparts specific biological activity.
• Chiral Synthesis: Utilized in asymmetric synthesis to introduce stereogenic centers, crucial for producing enantiomerically pure compounds.
• Fluorine Chemistry: Serves as a valuable substrate for studying structure-activity relationships (SAR) due to the presence of the fluorine atom.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.
• Academic & R&D: Employed in university and institutional research for exploring new synthetic methodologies and novel chemical entities.

Basic Information

Product Name	8-Fluoro-Chroman-4-Ylamine Hydrochloride
CAS No.	191608-18-1
Molecular Formula	C9H11ClFNO
Molecular Weight	203.64 g/mol
Synonyms	8-Fluorochroman-4-amine hydrochloride; 4-Amino-8-fluorochroman hydrochloride; 8-Fluoro-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride; (4-Amino-8-fluoro-3,4-dihydro-2H-chromen) hydrochloride; 191608-18-1; 8-Fluoro-4-chromanamine HCl; 8-Fluoro-2,3-dihydro-4H-1-benzopyran-4-amine hydrochloride
EINECS	Contact for details

Quality Control

Our 8-Fluoro-Chroman-4-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.