Description

6-Bromo-Chroman-4-Ylamine Hydrochloride is a high-purity organic building block and chiral amine derivative of significant interest in advanced pharmaceutical research and development. Its core value lies in its utility as a versatile synthetic intermediate for constructing complex molecular architectures. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications such as medicinal chemistry and the synthesis of bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and cardiovascular research.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization due to its bromo and amine functional groups.
• Agrochemical Synthesis: Serves as a precursor in the development of novel pesticides and herbicides.
• Fine Chemical Production: Employed in the custom synthesis of specialty chemicals and advanced materials.
• Academic Research: Utilized in universities and research institutes for methodological development and exploring new chemical transformations.
• Process Chemistry: Investigated for scalable synthesis routes in pilot plants and kilo-lab facilities.

Basic Information

Product Name	6-Bromo-Chroman-4-Ylamine Hydrochloride
CAS No.	191608-17-0
Molecular Formula	C9H11BrClNO
Molecular Weight	264.55 g/mol
Synonyms	4-Amino-6-bromochroman hydrochloride; 6-Bromo-3,4-dihydro-2H-1-benzopyran-4-amine hydrochloride; 6-Bromo-3,4-dihydro-2H-chromen-4-amine hydrochloride; 6-Bromochroman-4-amine HCl; (4-Amino-6-bromo-3,4-dihydro-2H-chromen-4-yl) hydrochloride; 6-Bromo-2,3-dihydro-4H-1-benzopyran-4-amine hydrochloride; 191608-17-0; 6-Bromo-4-chromanamine hydrochloride
EINECS	Contact for details

Quality Control

Our 6-Bromo-Chroman-4-Ylamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.