Description

(4S)-4-(2-Hydroxyethyl)-2-Phenyl-1,3-Dioxolane is a chiral dioxolane derivative, a versatile building block in fine chemical synthesis. Its value lies in its stereochemical purity and functional groups, which enable precise control in the synthesis of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop enantiomerically pure products.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, cardiovascular, and central nervous system (CNS) drug candidates.
• Asymmetric Synthesis: Used as a chiral auxiliary or precursor in stereoselective reactions to construct complex molecular architectures with high enantiomeric excess.
• Agrochemical Research: Serves as a building block for novel, enantiomerically pure pesticides and herbicides, where specific stereochemistry can influence biological activity.
• Ligand and Catalyst Development: A precursor for synthesizing chiral ligands used in transition metal catalysis, such as asymmetric hydrogenation or oxidation reactions.
• Flavor and Fragrance Industry: Potential intermediate for creating chiral aroma chemicals and flavor compounds where stereochemistry impacts sensory profile.
• Material Science: Can be utilized in the synthesis of chiral monomers for advanced polymers with specific optical or mechanical properties.

Basic Information

Product Name	(4S)-4-(2-Hydroxyethyl)-2-Phenyl-1,3-Dioxolane
CAS No.	191354-62-8
Molecular Formula	C11H14O3
Molecular Weight	194.23 g/mol
Synonyms	(4S)-2-Phenyl-4-(2-hydroxyethyl)-1,3-dioxolane; (S)-4-(2-Hydroxyethyl)-2-phenyl-1,3-dioxolane; (S)-2-Phenyl-4-(2-hydroxyethyl)-1,3-dioxolane; 4-(2-Hydroxyethyl)-2-phenyl-1,3-dioxolane (S-isomer); (S)-Styrene Glycol Acetonide; (S)-1,2-Isopropylidene Glycerol Benzyl Ether Derivative; (S)-Phenyl Dioxolane Ethanol
EINECS	Contact for details

Quality Control

Our (4S)-4-(2-Hydroxyethyl)-2-Phenyl-1,3-Dioxolane is produced under strict quality management systems. We ensure high chiral purity and chemical integrity through advanced analytical techniques. Certificates of Analysis (COA) detailing identity, purity (by HPLC), chiral excess, and impurity profiles are provided with every batch to support your research and cGMP compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.