Description

n-[(1S,2S)-2-Hydroxycyclohexyl]- Acetamide is a high-purity, stereochemically defined chiral acetamide derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block for the synthesis of complex organic molecules. It is primarily utilized by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries for developing new active ingredients and chiral catalysts.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Building block for creating advanced, enantiomerically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Catalyst Ligand Precursor: Used in the preparation of chiral ligands for asymmetric synthesis, enabling high enantioselectivity in hydrogenation and other key reactions.
• Fine Chemical Research: Serves as a starting material or intermediate in academic and industrial research for exploring new chemical entities and reaction pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke, multi-step synthesis projects requiring specific stereochemistry.

Basic Information

Product Name	n-[(1S,2S)-2-Hydroxycyclohexyl]- Acetamide
CAS No.	190848-36-3
Molecular Formula	C8H15NO2
Molecular Weight	157.21 g/mol
Synonyms	(1S,2S)-2-Acetamidocyclohexanol; trans-2-Acetamidocyclohexanol; N-[(1S,2S)-2-Hydroxycyclohexyl]acetamide; Acetamide, N-[(1S,2S)-2-hydroxycyclohexyl]-; (1S,2S)-N-(2-Hydroxycyclohexyl)acetamide; trans-N-(2-Hydroxycyclohexyl)acetamide; Chiral Cyclohexanol Acetamide Derivative
EINECS	Contact for details

Quality Control

Our n-[(1S,2S)-2-Hydroxycyclohexyl]- Acetamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard pharmacopeial identification tests, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, chiral excess, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.