Description

9-Fluorenylmethyl n-Hydroxycarbamate is a specialized carbamate derivative of 9-fluorenylmethanol, serving as a key synthetic intermediate and protecting group reagent. Its primary value lies in its utility for the reversible protection of hydroxyl groups in complex organic synthesis, particularly in the production of pharmaceuticals and fine chemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for sensitive synthetic pathways.

Application

• Pharmaceutical Intermediate: Used in the multi-step synthesis of active pharmaceutical ingredients (APIs), especially where selective hydroxyl protection is required.
• Peptide & Oligonucleotide Synthesis: Acts as a protecting group reagent for hydroxyl functionalities during solid-phase and solution-phase synthesis.
• Fine Chemical Production: Employed in the manufacture of complex organic molecules for agrochemicals, dyes, and liquid crystals.
• Academic & Industrial Research: A valuable tool for methodological development in organic chemistry and catalysis studies.
• Process Chemistry: Utilized in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Bioconjugation Chemistry: Can be used to modify biomolecules, creating probes or drug conjugates for biochemical research.

Basic Information

Product Name	9-Fluorenylmethyl n-Hydroxycarbamate
CAS No.	190656-01-0
Molecular Formula	C₁₅H₁₃NO₃
Molecular Weight	255.27 g/mol
Synonyms	9-Fluorenylmethyl N-hydroxycarbamate; FMOC-NH-OH; N-Hydroxy-9H-fluoren-9-ylmethoxycarboxamide; 9-Fluorenylmethoxycarbonyl hydroxylamine; Fmoc-hydroxylamine; Fmoc-NHOH; (9H-Fluoren-9-yl)methyl N-hydroxycarbamate; Hydroxycarbamic acid 9H-fluoren-9-ylmethyl ester
EINECS	Contact for details

Quality Control

Our 9-Fluorenylmethyl n-Hydroxycarbamate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for assay and purity, and is accompanied by a detailed Certificate of Analysis (COA). We support compliance with cGMP and ICH guidelines for pharmaceutical applications, and specifications can be tailored to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent decomposition. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Purity (HPLC)	≥97.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.