Description

2-Amino-7-Fluoroquinazoline is a high-purity, fluorinated quinazoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly kinase inhibitors and other targeted therapeutics. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to incorporate its unique fluorinated quinazoline scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the biological activity of the quinazoline core.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating molecular probes to study enzyme function and cellular signaling processes.
• Material Science Research: Investigated as a building block for organic electronic materials and advanced polymers due to its fused heterocyclic structure.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.
• Academic & Institutional Research: Utilized in university and government labs for fundamental studies in medicinal chemistry and heterocyclic compound reactivity.

Basic Information

Product Name	2-Amino-7-Fluoroquinazoline
CAS No.	190274-01-2
Molecular Formula	C8H5FN4
Molecular Weight	176.15 g/mol
Synonyms	7-Fluoro-2-quinazolinamine; 7-Fluoroquinazolin-2-amine; 2-Amino-7-fluoroquinazoline; 190274-01-2; 7-Fluoro-2-aminoquinazoline; Quinazoline, 2-amino-7-fluoro-; 2-Quinazolinamine, 7-fluoro-; 7-Fluoro-1,3-diazanaphthalen-2-amine
EINECS	Contact for details

Quality Control

Our 2-Amino-7-Fluoroquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.