Description

6-(Trifluoromethyl)Quinazolin-2-Amine is a high-value, fluorinated quinazoline derivative serving as a critical building block in advanced organic synthesis. Its core value lies in the trifluoromethyl group, which is strategically incorporated to modulate the physicochemical and pharmacokinetic properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Agrochemical Research: Used in developing new herbicides and fungicides with improved efficacy and environmental profiles.
• Material Science: Serves as a monomer or additive for creating specialty polymers with unique electronic or surface properties.
• Chemical Biology: Employed as a molecular probe or scaffold in drug discovery and biochemical assay development.
• Organic Light-Emitting Diodes (OLEDs): Investigated as an electron-transport or emissive layer component due to its fluorinated aromatic structure.

Basic Information

Product Name	6-(Trifluoromethyl)Quinazolin-2-Amine
CAS No.	190273-94-0
Molecular Formula	C9H6F3N3
Molecular Weight	213.16 g/mol
Synonyms	2-Amino-6-(trifluoromethyl)quinazoline; 6-(Trifluoromethyl)-2-quinazolinamine; Quinazolin-2-amine, 6-(trifluoromethyl)-; 190273-94-0; 6-Trifluoromethylquinazolin-2-ylamine
EINECS	Contact for details

Quality Control

Our 6-(Trifluoromethyl)Quinazolin-2-Amine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.