Description

2-Amino-5-Fluoroquinazoline is a high-purity, fluorinated quinazoline derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents, particularly in kinase inhibitor research and targeted cancer therapies. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality intermediates for their synthetic pathways.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of tyrosine kinase inhibitors and other targeted therapeutic molecules.
• Agrochemical Research: Used in the development of new herbicides and fungicides with specific modes of action.
• Chemical Biology Probes: Serves as a scaffold for creating fluorescent tags or activity-based probes to study enzyme function.
• Material Science: Potential building block for organic electronic materials and liquid crystals due to its planar, heterocyclic structure.
• Academic & Contract Research: Employed in university and CRO laboratories for method development and novel compound library synthesis.

Basic Information

Product Name	2-Amino-5-Fluoroquinazoline
CAS No.	190273-81-5
Molecular Formula	C8H6FN3
Molecular Weight	163.15 g/mol
Synonyms	5-Fluoro-2-quinazolinamine; 5-Fluoroquinazolin-2-amine; 2-Amino-5-fluoroquinazoline; 190273-81-5; 5-Fluoro-2-aminoquinazoline; Quinazoline, 2-amino-5-fluoro-; 2-Quinazolinamine, 5-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Fluoroquinazoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.