Description

2-Amino-5-Chloroquinazoline is a high-purity, versatile heterocyclic building block essential for advanced organic synthesis. This compound matters as a critical intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals, offering a reactive scaffold for further functionalization. It is primarily needed by research and development chemists, pharmaceutical manufacturers, and agrochemical companies for creating novel compounds with targeted biological activity.

Application

• Key synthetic intermediate in the research and production of pharmaceutical compounds, particularly kinase inhibitors and other small-molecule drugs.
• Building block for the development of agrochemicals, including potential herbicides and fungicides.
• Precursor in the synthesis of complex heterocyclic compounds for material science and chemical research.
• Used in academic and industrial R&D for exploring new chemical entities and reaction pathways.
• Intermediate for creating dyes and pigments with specialized properties.
• Starting material for the preparation of coordination compounds and ligands in catalysis.

Basic Information

Product Name	2-Amino-5-Chloroquinazoline
CAS No.	190273-70-2
Molecular Formula	C8H6ClN3
Molecular Weight	179.61 g/mol
Synonyms	5-Chloro-2-quinazolinamine; 5-Chloro-2-aminoquinazoline; 5-Chloroquinazolin-2-amine; 2-Amino-5-chloro-quinazoline; 190273-70-2; Quinazoline, 2-amino-5-chloro-; 2-Quinazolinamine, 5-chloro-
EINECS	Contact for details

Quality Control

Our 2-Amino-5-Chloroquinazoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and meet stringent impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.